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Spaglumic acid

Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic Acid is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes.

Product Specifications

CAS Number

3106-85-2

Product Name Alternative

NAAG, N-Acetylaspartylglutamic acid

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Water:29 mg/mL (95.31 mM)

Smiles

CC (=O) N[C@@H] (CC (O) =O) C (=O) N[C@@H] (CCC (O) =O) C (O) =O

Molecular Formula

C11H16N2O8

Molecular Weight

304.26

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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