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Poziotinib hydrochloride

Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.

Product Specifications

CAS Number

1429757-68-5

Product Name Alternative

NOV120101 hydrochloride, HM 781-36B hydrochloride

Purity

>98% (HPLC)

Smiles

Cl.COc1cc2ncnc (Nc3ccc (Cl) c (Cl) c3F) c2cc1OC1CCN (CC1) C (=O) C=C

Molecular Formula

C23H22Cl3FN4O3

Molecular Weight

527.8

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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