Poziotinib hydrochloride
Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
Product Specifications
CAS Number
1429757-68-5
Product Name Alternative
NOV120101 hydrochloride, HM 781-36B hydrochloride
Purity
>98% (HPLC)
Smiles
Cl.COc1cc2ncnc (Nc3ccc (Cl) c (Cl) c3F) c2cc1OC1CCN (CC1) C (=O) C=C
Molecular Formula
C23H22Cl3FN4O3
Molecular Weight
527.8
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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