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BMS-P5 free base

BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-P5 to multiple myeloma-bearing mice delays appearance of symptoms and disease progression Targeting PAD4 may be beneficial for treatment of multiple myeloma.Administration of BMS-P5 to multiple myeloma-bearing mice delays appearance of symptoms and disease progression.

Product Specifications

CAS Number

1550371-22-6

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 250 mg/mL (529.01 mM)

Smiles

O=C (N1[C@@H] (C) CC[C@@H] (N) C1) C2=CC (OC) =C3C (N=C (C4=CC5=CC=CN=C5N4CC6CC6) N3C) =C2

Molecular Formula

C27H32N6O2

Molecular Weight

472.58

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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