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GSK620

GSK620 is a pan-BD2 inhibitor, which shows an anti-inflammatory phenotype in human whole blood with excellent broad selectivity, developability, and in vivo oral pharmacokinetics.GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood.

Product Specifications

CAS Number

2088410-46-0

Purity

>98% (HPLC)

Solubility

DMSO:62.5 mg/mL (192.09 mM; Need ultrasonic)

Smiles

CNC (=O) C1=CC (=CN (C1=O) CC2=CC=CC=C2) C (=O) NC3CC3

Molecular Formula

C18H19N3O3

Molecular Weight

325.4

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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