API-1
API-1 is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
Product Specifications
CAS Number
36707-00-3
Product Name Alternative
NSC177223
Purity
>98% (HPLC)
Solubility
DMSO:10 mM
Smiles
C1=C (C (=O) C2=C (N=CN=C2N1[C@H]3[C@@H] ([C@@H] ([C@H] (O3) CO) O) O) N) C (=O) N
Molecular Formula
C13H15N5O6
Molecular Weight
337.29
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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