NU6140
NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM) . It shows 10- to 36-fold selectivity over other CDKs. NU6140 also effectively inhibits Aurora A and Aurora B (IC50s: 67 and 35 nM, respectively) . It also enhances the apoptotic effect and has anti-cancer activity.
Product Specifications
CAS Number
444723-13-1
Purity
>98% (HPLC)
Solubility
DMSO:250 mg/mL (591.69 mM; Need ultrasonic)
Smiles
CCN (CC) C (C (C=C1) =CC=C1NC2=NC (OCC3CCCCC3) =C4C (N=CN4) =N2) =O
Molecular Formula
C23H30N6O2
Molecular Weight
422.52
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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