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RO-0335

RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.

Product Specifications

CAS Number

867365-76-2

Purity

>98% (HPLC)

Solubility

DMSO:200mg/ml (348.91mM; need ultrasonic)

Smiles

NS (c (cc1) cc (Cl) c1NC (Cc (ccc (Br) c1Oc2cc (Cl) cc (C#N) c2) c1F) =O) (=O) =O

Molecular Formula

C21H13BrCl2FN3O4S

Molecular Weight

573.22

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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