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PGpG

The linear diguanylate pGpG is the first phosphodiesterase-catalyzed hydrolysis product of cylic di-GMP (c-diGMP) . C-diGMP has been identified as a novel second messenger in bacteria that triggers various physiological changes such as virulence gene expression or cell differentiation. The role of pGpG in c-diGMP signalling is under investigation.

Product Specifications

CAS Number

33008-99-0

Product Name Alternative

P1- (5'-Guanosyl) -P2- (5'-guanosyl) - (3'→5') -diphosphate, Sodium salt

Purity

≥ 95% (HPLC)

Form

Solid; Color: white to off-white

Smiles

O[C@H]1[C@H] (n2cnc3c (=O) [nH]c (N) nc23) O[C@H] (COP (=O) (O) O) [C@H]1OP (=O) (OC[C@H]1O[C@@H] (n2cnc3c (=O) [nH]c (N) nc23) [C@H] (O) [C@@H]1O) O

Molecular Formula

C20H26N10O15P2

Molecular Weight

Theoretical MW: 708.43 g/mol (free acid) ; Detected MW: 708.11 g/mol (free acid)

Storage Conditions

Store at -20 °C

Notes

For research use only.

Applications Notes

Spectroscopic Propertie: λmax 252 nm, ε 25.0 L mmol-1 cm-1 (Tris-HCl, pH 7.5) .

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