MC-Val-Cit-PAB-Ispinesib
Product Specifications
UNSPSC Description
MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent inhibitor of Eg5. MC-Val-Cit-PAB-Ispinesib is a click chemistry reagent[1].
Target Antigen
Kinesin
Type
ADC Related
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-val-cit-pab-ispinesib.html
Solubility
Chloroform : ≥ 100 mg/mL
Smiles
O=C(C1=CC=C(C=C1)C)N(CCCNC(OCC2=CC=C(C=C2)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)=O)[C@@H](C(N4CC5=CC=CC=C5)=NC6=CC(Cl)=CC=C6C4=O)C(C)C
Molecular Weight
1115.71
References & Citations
[1]Paul A. Barsanti, et al. Cell proliferation inhibitors and conjugates thereof. WO2014151030. 2014-09-25
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160441/MC-Val-Cit-PAB-Ispinesib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160441/MC-Val-Cit-PAB-Ispinesib-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
1629737-40-1
Available Sizes
Curated Selection
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