MC-Val-Cit-PAB-Ispinesib
MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent inhibitor of Eg5. MC-Val-Cit-PAB-Ispinesib is a click chemistry reagent[1].
Product Specifications
CAS Number
1629737-40-1
UNSPSC
12352203
Target
Kinesin
Type
ADC Related
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-val-cit-pab-ispinesib.html
Purity
99.85
Solubility
Chloroform : ≥ 100 mg/mL|DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C=C1)C)N(CCCNC(OCC2=CC=C(C=C2)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)=O)[C@@H](C(N4CC5=CC=CC=C5)=NC6=CC(Cl)=CC=C6C4=O)C(C)C
Molecular Formula
C59H71ClN10O10
Molecular Weight
1115.71
References & Citations
[1]Paul A. Barsanti, et al. Cell proliferation inhibitors and conjugates thereof. WO2014151030. 2014-09-25
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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