SPTC2 rabbit pAb
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011],
Product Specifications
Background
Synonyms
Gene ID
9517
UniProt
O15270
Cellular Locus
Endoplasmic reticulum membrane ; Single-pass membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human SPTC2 AA range: 273-323
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000
Molecular Weight
60kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES12972-1.pdf
Observed Molecular Weight
60 kD
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass membrane protein .
Other Product Names
Gene ID (Human)
9517
SwissProt (Human)
O15270
Available Sizes
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