IUB0271

IUB0271 (acyl-GIP) is a long-acting acylated glucose-dependent insulinotropic polypeptide (GIP) . It enhances cFos neuronal activity in the hypothalamic feeding centers of DIO mouse models and reduces body weight, food intake, and blood glucose levels, effects dependent on CNS-GIPR signaling. IUB0271 is applicable in research on type 2 diabetes (T2DM) and obesity.