Pentixather

Pentixather is a radiolabeled peptide that targets CXCR4. By disrupting the interaction between leukemia cells and the bone marrow microenvironment through targeting the CXCR4/CXCL12 signaling axis, Pentixather reduces the retention of leukemia cells in protective bone marrow niches, thereby increasing their sensitivity to treatment. It is applicable in studies related to acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) .