PA2-GNU7

PA2-GNU7 is an antimicrobial peptide (AMP) with potent antibacterial activity, demonstrating minimum inhibitory concentrations (MIC) of 2 μM for Pseudomonas aeruginosa, 1 μM for Escherichia coli, 2 μM for Salmonella, 2 μM for Staphylococcus aureus, and 8 μM for Candida albicans. It rapidly and selectively kills Pseudomonas aeruginosa without affecting other symbiotic bacteria and significantly enhances the survival rate of mice infected with Pseudomonas aeruginosa. PA2-GNU7 has potential applications in researching and developing treatments for infections caused by multidrug-resistant Pseudomonas aeruginosa.