NC-002

NC-002 is a cell-penetrating peptide and functions as an inhibitor of the trypsin-like proteasome (Trypsin-likeproteasome), without affecting the activity of lysosomal cysteine proteases. It is an epoxyketone derivative of Leupeptin. NC-002 enhances the sensitivity of myeloma cells to Bortezomib and Carfilzomib and is utilized in cancer research.