Human ALK-7 Protein, Fc Tag (MALS verified)
ALK-7, also known as ACVR1C , is a Type I receptor for the TGF-beta family of signaling molecules. Upon ligand binding, it initiates intracellular signaling by phosphorylating cytoplasmic SMAD transcription factors. These activated SMADs then translocate to the nucleus to regulate gene expression, either directly or in complex with other transcription factors.
Product Specifications
Expression Region
Glu 21 - Glu 113
Reactivity
Human
Conjugation
Unconjugated
Tag
C-Fc
Field of Research
Immunology & Inflammation; Cell Biology
Purity
90%
Form
Powder
Molecular Weight
36.5 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 36.5 kDa. The protein migrates as 43-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
Q8NER5
Preservative
20 mM Tris, 150 mM NaCl, pH 7.5
Available Sizes
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