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Bat coronavirus RS4081 Spike Trimer Protein (R653A, K954P, V955P), His Tag (MALS verified)

The spike protein of bat coronavirus RS4081, a sarbecovirus related to SARS-CoV, mediates viral entry by facilitating attachment and membrane fusion. RS4081’s spike can support ACE2-independent, trypsin-dependent cell entry, highlighting alternative pathways for host infection and its potential relevance to zoonotic spillover and cross-species transmission studies.

Product Specifications

Expression Region

Gln 16 - Pro 1181

Conjugation

Unconjugated

Tag

C-10xHis

Field of Research

Immunology & Inflammation; Metabolism Research

Endotoxin

1.0 EU per μg

Purity

90%

Form

Powder

Molecular Weight

134.9 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 134.9 kDa. The protein migrates as 150-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

ATO98120.1, V955, R653, K954

Preservative

0.1 M Sodium citrate, pH 5.5

Available Sizes

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