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Cynomolgus Kallikrein 3 Protein, His Tag (active enzyme, MALS verified)

Kallikrein-related peptidase 3, more commonly known as Kallikrein 3 (KLK3) or Prostate-Specific Antigen (PSA), is a serine protease belonging to the kallikrein family. Its primary function is to cleave proteins, and it is a key biomarker for prostate cancer. Secreted by the epithelial cells of the prostate gland, elevated levels of KLK3 in the blood are often indicative of prostate pathologies, including benign prostatic hyperplasia and prostate cancer. Beyond its role as a diagnostic marker, recent research explores its potential as a therapeutic target in cancer treatment. Its unique expression pattern and enzymatic function make it a subject of extensive research in oncology.

Product Specifications

Expression Region

Pro 19 - Pro 261

Reactivity

Monkey

Conjugation

Unconjugated

Tag

C-10xHis

Field of Research

Immunology & Inflammation

Endotoxin

1.0 EU per μg

Purity

95%

Form

Powder

Molecular Weight

28.7 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.7 kDa. The protein migrates as 30-35 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

Q6DT45

Preservative

50 mM Tris, 150 mM NaCl, pH 7.5

Available Sizes

Frequently Asked Questions

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