Cynomolgus IRAK4 Protein, His Tag (active enzyme)
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Specifications
Expression Region
Met 1 - Ser 460
Reactivity
Monkey
Conjugation
Unconjugated
Tag
N-10xHis
Field of Research
Immunology & Inflammation
Endotoxin
1.0 EU per μg
Purity
90%
Form
Liquid
Molecular Weight
53.6 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 53.6 kDa. The protein migrates as 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
A0A2K5V3Y9
Preservative
50 mM HEPES, 300 mM NaCl, pH 7.5
Available Sizes
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