Human IL-1 beta / IL-1F2 Protein, Research Grade
Interleukin-1 beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties; The mature human IL1β shares 96 % amino acid sequence identity with rhesus and 67 % -78 % with canine, mouse and rat IL-1β.
Product Specifications
Expression Region
Ala 117 - Ser 269
Reactivity
Human
Conjugation
Unconjugated
Tag
Native
Field of Research
Immunology & Inflammation
Endotoxin
0.01 EU per μg
Purity
95%
Form
Powder
Molecular Weight
17.5 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries no "tag". The protein has a calculated MW of 17.5 kDa. The protein migrates as 18 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .
NCBI Accession Number
P01584
Preservative
PBS, pH 7.4
Available Sizes
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