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Human IL-1RA Protein, Tag Free (MALS verified)

Interleukin-1 receptor antagonist (IL-1RA) is a naturally occurring anti-inflammatory antagonist of interleukin-1 family of pro-inflammatory cytokines. It competes with IL-1α and IL-1β to bind IL-1R1, thereby acting as an endogenous inhibitor of the IL-1 signaling pathway. IL‐1RA has been connected with a variety of diseases, including cardiovascular disease, type II diabetes, carcinoma, and joint diseases.

Product Specifications

Expression Region

Arg 26 - Glu 177

Reactivity

Human

Conjugation

Unconjugated

Tag

Native

Field of Research

Immunology & Inflammation

Endotoxin

1.0 EU per μg

Purity

95%

Form

Powder

Molecular Weight

17.3 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries no "tag". The protein has a calculated MW of 17.3 kDa. The protein migrates as 15-16 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .

NCBI Accession Number

P18510

Preservative

PBS, pH 7.4

Available Sizes

Frequently Asked Questions

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