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Human Cadherin-17 / CDH17 (23-667) Protein, His Tag (MALS verified)

Selected Variant

GTR19149797-01

Size: 1 mg

Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Product Specifications

Expression Region

Gln 23 - Leu 667

Reactivity

Human

Conjugation

Unconjugated

Tag

C-10xHis

Field of Research

Immunology & Inflammation

Endotoxin

1.0 EU per μg

Purity

95%

Form

Powder

Molecular Weight

73.7 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 73.7 kDa. The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

Q12864

Preservative

20 mM Tris, 150 mM NaCl, pH 8.0

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