Human Cadherin-17 / CDH17 (450-566) Protein, Fc Tag (MALS verified)
Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Specifications
Expression Region
Glu 450 - Phe 566
Reactivity
Human
Conjugation
Unconjugated
Tag
C-Fc
Field of Research
Immunology & Inflammation
Endotoxin
1.0 EU per μg
Purity
95%
Form
Powder
Molecular Weight
39.1 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 39.1 kDa. The protein migrates as 43-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
Q12864
Preservative
20 mM Tris, 150 mM NaCl, pH 8.0
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