Human BTK (1-659) Protein, His Tag (active enzyme, HPLC verified)
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Specifications
Expression Region
Met 1 - Ser 659
Reactivity
Human
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Cell Biology
Endotoxin
1.0 EU per μg
Purity
90%
Form
Liquid
Molecular Weight
78.2 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 78.2 kDa . The protein migrates as 57 kDa and 75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .
NCBI Accession Number
Q06187
Preservative
50 mM Tris, 150 mM NaCl, pH 7.5
Available Sizes
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