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Human BMP-4 / BMP2B Protein, Research Grade

Bone Morphogenetic Protein 4 (BMP4) is a member of growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. BMP-4 Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. BMP-4 can acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

Product Specifications

Expression Region

Ser 293 - Arg 408

Reactivity

Human

Conjugation

Unconjugated

Tag

Native

Field of Research

Stem Cell & Developmental Biology

Endotoxin

0.01 EU per μg

Purity

95%

Form

Powder

Molecular Weight

13.1 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries no "tag". The protein has a calculated MW of 13.1 kDa. The protein migrates as 21 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

NP_001193.2

Preservative

20 mM Citric acid, pH 2.2

Available Sizes

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