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Human Tau-352 / 0N3R Protein, Tag Free, low Endotoxin (MALS verified)

Selected Variant

GTR19149774-01

Size: 100 µg

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Product Specifications

Expression Region

Met 1 - Leu 352

Reactivity

Human

Conjugation

Unconjugated

Tag

Native

Field of Research

Neuroscience; Immunology & Inflammation

Endotoxin

0.01 EU per μg

Purity

95%

Form

Liquid

Molecular Weight

36.8 kDa

Storage Conditions

-70°C

Notes

For research use only.

Applications Notes

This protein carries no "tag". The protein has a calculated MW of 36.8 kDa. The protein migrates as 38 kDa, 40 kDa and 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

P10636

Preservative

20 mM Tris, 150 mM NaCl, pH 7.5

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