Human ADAM10 Protein, His Tag (active enzyme)
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016]
Product Specifications
Expression Region
Thr 214 - Glu 672
Reactivity
Human
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Neuroscience
Endotoxin
1.0 EU per μg
Purity
90%
Form
Liquid
Molecular Weight
52.5 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 52.5 kDa. The protein migrates as 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
O14672
Preservative
20 mM Tris, 500 mM NaCl, pH 7.5
Available Sizes
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