Aspergillus fumigatus Dihydroorotate Dehydrogenase Protein, His Tag
Aspergillus fumigatus dihydroorotate dehydrogenase (DHODH) is an essential mitochondrial enzyme in the de novo pyrimidine biosynthesis pathway, required for fungal DNA and RNA synthesis. Because A. fumigatus relies on DHODH for growth and survival, the enzyme has emerged as a validated antifungal drug target, exemplified by inhibitors such as olorofim
Product Specifications
UniProt
A0A229W7A4
Expression Region
Ala 89 - Gln 531
Reactivity
Aspergillus
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Metabolism Research
Purity
90%
Form
Liquid
Molecular Weight
49.5 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 49.5 kDa. The protein migrates as 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .
NCBI Accession Number
A0A229W7A4
Preservative
50 mM Tris, 150 mM NaCl, pH 8.0
Available Sizes
Frequently Asked Questions
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