Human FASN Protein, His Tag (active enzyme)
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
Product Specifications
Expression Region
Leu 2200 - Gly 2511
Reactivity
Human
Conjugation
Unconjugated
Tag
N-10xHis
Field of Research
Signal Transduction; Protein Biochemistry
Purity
95%
Form
Liquid
Molecular Weight
58.3 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 58.3 kDa. The protein migrates as 34-39 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .
NCBI Accession Number
NP_004095
Preservative
20 mM Tris, 500 mM NaCl, pH 7.9
Available Sizes
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