Human USP7 Protein, His Tag
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental
Product Specifications
UniProt
Q93009
Expression Region
Asn 2 - Asn 1102
Reactivity
Human
Conjugation
Unconjugated
Tag
N-10xHis
Field of Research
Epigenetics & Chromatin
Endotoxin
1.0 EU per μg
Purity
85%
Form
Liquid
Molecular Weight
130.2 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 130.2 kDa. The protein migrates as 130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .
NCBI Accession Number
Q93009
Preservative
50 mM HEPES, 100 mM NaCl, pH 8.0
Available Sizes
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