Human Prostatic Acid Phosphatase Protein, His Tag (active enzyme, MALS verified)
Prostatic acid phosphatase also know as acid phosphatase 3 (ACP3), it is a non-specific tyrosine phosphatase that acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling. In addition to its tyrosine phosphatase activity has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor.
Product Specifications
UniProt
P15309
Expression Region
Lys 33 - Lys 382
Reactivity
Human
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Immunology & Inflammation
Endotoxin
1.0 EU per μg
Purity
90%
Form
Liquid
Molecular Weight
42.5 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.5 kDa. The protein migrates as 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
P15309
Preservative
100 mM NaAC, pH 5.0
Available Sizes
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