Mouse IRAK4 Protein, His Tag (active enzyme)
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Specifications
UniProt
Q8R4K2
Expression Region
Met 1 - Ala 459
Reactivity
Mouse
Conjugation
Unconjugated
Tag
N-10xHis
Field of Research
Immunology & Inflammation
Endotoxin
1.0 EU per μg
Form
Liquid
Molecular Weight
52.9 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 52.9 kDa.
NCBI Accession Number
Q8R4K2
Preservative
50 mM Tris, 150 mM NaCl, pH 7.5
Available Sizes
Frequently Asked Questions
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