MitoBloCK-6
Product Specifications
UNSPSC Description
MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mitoblock-6.html
Purity
98.07
Solubility
DMSO : 50 mg/mL (ultrasonic;warming)
Smiles
OC1=C(/C=N/C2=CC=C(NC3=CC=CC=C3)C=C2)C=C(Cl)C=C1Cl
Molecular Weight
357.23
References & Citations
[1]Dabir DV, et, al. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15;25(1):81-92.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122652/MitoBloCK-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122652/MitoBloCK-6-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
303215-67-0
Available Sizes
Curated Selection
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