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PEG3-C4-OBn

PEG3-C4-OBn is a polyethylene glycol (PEG) -based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1. PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC[1][2].

Product Specifications

CAS Number

2381196-79-6

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/peg3-c4-obn.html

Purity

99.29

Solubility

DMSO : ≥ 100 mg/mL

Smiles

OCCOCCOCCCCCCOCC1=CC=CC=C1

Molecular Formula

C17H28O4

Molecular Weight

296.41

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14 (9) :2024-2034.|[2]Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 5.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Frequently Asked Questions

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