Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Dorzagliatin (Standard)

Dorzagliatin (Standard) is the analytical standard of Dorzagliatin. This product is intended for research and analytical applications. Dorzagliatin (HMS5552), a dual-acting glucokinase (GK) activator, improves glycaemic control and pancreatic β-cell function in type 2 diabetes[1].

Product Specifications

CAS Number

[1191995-00-2]

Product Name Alternative

HMS5552 (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Glucokinase; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/dorzagliatin-standard.html

Purity

98.47

Smiles

O=C([C@H](CC(C)C)N1CC(OC2=C(Cl)C=CC=C2)=CC1=O)NC3=NN(C=C3)C[C@H](CO)O

Molecular Formula

C22H27ClN4O5

Molecular Weight

462.93

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhu XX, et al. Dorzagliatin (HMS5552), a novel dual-acting glucokinase activator, improves glycaemic control and pancreatic β-cell function in patients with type 2 diabetes: A 28-day treatment study using biomarker-guided patient selection. Diabetes Obes Metab. 2018 Sep;20 (9) :2113-2120.|[2]Wang P, et al. Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus. J Diabetes Res. 2017;2017:5812607.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, sealed storage, away from light and moisture

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-109030R/Dorzagliatin-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-109030R/Dorzagliatin-Standard-SDS-MedChemExpress.pdf

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Bcl x (BCL2L1) (NM_138578) Human Over-expression Lysate
LC403363 20 µg

Bcl x (BCL2L1) (NM_138578) Human Over-expression Lysate

Ask
View Details
PIC 281-DIA 200-B7527 Personal Protection (PPE) Signs (No Adhesive)
252161 1 Card (1 Panel (s) x 1 Pack)

PIC 281-DIA 200-B7527 Personal Protection (PPE) Signs (No Adhesive)

Ask
View Details
Biotin-Linked Polyclonal Antibody to Macrophage Derived Chemokine (MDC)
MBS2091527-01 0.1 mL

Biotin-Linked Polyclonal Antibody to Macrophage Derived Chemokine (MDC)

Ask
View Details
Biotin-Linked Polyclonal Antibody to Macrophage Derived Chemokine (MDC)
MBS2091527-02 0.2 mL

Biotin-Linked Polyclonal Antibody to Macrophage Derived Chemokine (MDC)

Ask
View Details
Biotin-Linked Polyclonal Antibody to Macrophage Derived Chemokine (MDC)
MBS2091527-03 0.5 mL

Biotin-Linked Polyclonal Antibody to Macrophage Derived Chemokine (MDC)

Ask
View Details
Biotin-Linked Polyclonal Antibody to Macrophage Derived Chemokine (MDC)
MBS2091527-04 1 mL

Biotin-Linked Polyclonal Antibody to Macrophage Derived Chemokine (MDC)

Ask
View Details