CDK9-IN-10

CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811) [1].

Product Specifications

CAS Number

[3542-63-0]

UNSPSC

12352005

Target

CDK; Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; PROTAC

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk9-in-10.html

Purity

98.09

Solubility

DMSO : ≥ 100 mg/mL

Smiles

OC1=C2C(C(C=C(C3=CC=CC=C3)O2)=O)=C(O)C=C1OCC4=CC=CC=C4

Molecular Formula

C22H16O5

Molecular Weight

360.36

References & Citations

[1]Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK9

Available Sizes

Curated Selection

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