F0045 (S)
F0045 (S) is a potent influenza hemagglutinin inhibitor with a KD value of 6.1 µM. F0045 (S) protects human cells from influenza infection[1][2].
Product Specifications
CAS Number
2716077-17-5
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/f0045-s.html
Smiles
O=C(N1CCO[C@@H](C2=CC=CC=C2)C1)C3=CC=C(Cl)C=C3Cl
Molecular Formula
C17H15Cl2NO2
Molecular Weight
336.21
References & Citations
[1]Kitamura S, et al. Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc Natl Acad Sci U S A. 2024 May 28;121 (22) :e2310677121.|[2]Yao Y, et al. An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen. Proc Natl Acad Sci U S A. 2020 Aug 4;117 (31) :18431-18438.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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