GNF351
Product Specifications
UNSPSC Description
GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes[1].
Target Antigen
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gnf351.html
Purity
99.90
Solubility
DMSO : ≥ 125 mg/mL
Smiles
CC1=CN=CC(C2=NC(NCCC3=CNC4=C3C=CC=C4)=C5N=CN(C(C)C)C5=N2)=C1
Molecular Weight
411.50
References & Citations
[1]van den Bogaard EH, et al. Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation. J Invest Dermatol. 2015 May;135(5):1320-1328.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-102023/GNF351-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-102023/GNF351-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1227634-69-6
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Recombinant Halobacterium salinarum Superoxide dismutase [Mn] 2 (sod2)](https://cdn.genprice.uk/genprice/genprice2.png)
MBS1017360-01 0.02 mg (E-Coli)
Recombinant Halobacterium salinarum Superoxide dismutase [Mn] 2 (sod2)
Ask
View Details MBS1017360-02 0.1 mg (E-Coli)
Recombinant Halobacterium salinarum Superoxide dismutase [Mn] 2 (sod2)
Ask
View Details MBS1017360-03 0.02 mg (Yeast)
Recombinant Halobacterium salinarum Superoxide dismutase [Mn] 2 (sod2)
Ask
View Details