RepSox (GMP)
RepSox (E-616452) (GMP) is a RepSox produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor[1].
Product Specifications
CAS Number
446859-33-2
Product Name Alternative
E-616452 (GMP) ; SJN 2511 (GMP)
UNSPSC
12352005
Hazard Statement
H301
Target
TGF-β Receptor
Type
GMP Small Molecules
Related Pathways
TGF-beta/Smad
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/repsox-gmp.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
CC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1
Molecular Formula
C17H13N5
Molecular Weight
287.32
Precautions
H301
References & Citations
[1]Zhao T, et al. Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming. Cell Stem Cell. 2018 Jul 5;23 (1) :31-45.e7. |[2]Guan J, et al. Chemical reprogramming of human somatic cells to pluripotent stem cells. Nature. 2022 May;605 (7909) :325-331. |[3]Bar-Nur O, et al. Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors. Stem Cell Reports. 2018 May 8;10 (5) :1505-1521.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from moisture and light
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TRC-C315018-5G 5 g
Chitosan Oligosaccharide Hydrochloride Salt (Technical Grade)
Sign In for Pricing
View Details 
![(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(3R)-3-pyrrolidinylthio]-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid (>90%)](https://cdn.genprice.uk/products/572/5494831375458/imageurl/trc-h943013-2.5mg.webp)
TRC-H943013-2.5MG 2.5 mg
(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(3R)-3-pyrrolidinylthio]-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid (>90%)
Sign In for Pricing
View Details