Argatroban
Argatroban (MD-805) is a direct, selective thrombin inhibitor.
Product Specifications
CAS Number
74863-84-6
Product Name Alternative
MD-805; MCI-9038
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/argatroban.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1N(C([C@@H](NS(=O)(C2=CC=CC3=C2NCC(C)C3)=O)CCCNC(N)=N)=O)CC[C@@H](C)C1)O
Molecular Formula
C23H36N6O5S
Molecular Weight
508.63
Precautions
H302, H315, H319, H335
References & Citations
[1]Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47 (3) : p. 104-9.|[2]Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33 (7) : p. 1879-85.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Biomed Pharmacother. 2025 Apr 28:187:118104.|Int Immunopharmacol. 2025 Apr 4:151:114334.|Int J Mol Sci. 2021 Mar 24;22 (7) :3323.|University of Bonn. 2023 May 31.|Antiviral Res. 2023 Jun:214:105606.
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