WYC-209
Product Specifications
UNSPSC Description
WYC-209, a synthetic retinoid, is a retinoic acid receptor (RAR) agonist. WYC-209 induces apoptosis primarily via the caspase 3 pathway (IC50=0.19?μM for inmalignant murine melanoma TRCs), and has long-term effects with little toxicity[1].
Target Antigen
Apoptosis; Autophagy; RAR/RXR
Type
Reference compound
Related Pathways
Apoptosis;Autophagy;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wyc-209.html
Purity
98.68
Solubility
DMSO : 83.33 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
Smiles
O=C(C1=CN=C(C#CC2=CC=C3C(C(C)(C)CCS3=O)=C2)N=C1)OCC
Molecular Weight
368.45
References & Citations
[1]Chen J, et al. Inhibition of cancer stem cell like cells by a synthetic retinoid. Nat Commun. 2018 Apr 11;9(1):1406.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124136/WYC-209-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124136/WYC-209-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2131803-90-0
Available Sizes
Curated Selection
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