Radequinil

Radequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 binds to GABA (-) and GABA (+) ligand with Kis of 5.15 and 6.11 nM, respectively[1].

Product Specifications

CAS Number

[219846-31-8]

Product Name Alternative

AC-3933

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/radequinil.html

Purity

99.25

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1NC2=CC=NC(C3=CC(OC)=CC=C3)=C2C=C1C4=NOC(C)=N4

Molecular Formula

C18H14N4O3

Molecular Weight

334.33

References & Citations

[1]Hashimoto T, et al. Pharmacological properties of AC-3933, a novel benzodiazepine receptor partial inverse agonist. Neuroscience. 2014 Jan 3;256:352-9.