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Telratolimod

Telratolimod (MEDI9197) is a potent toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity[1].

Product Specifications

CAS Number

1359993-59-1

Product Name Alternative

MEDI9197; 3M-052

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Telratolimod.html

Purity

98.85

Solubility

DMSO : 62.5 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC1=NC2=CC=CC=C2C3=C1N=C(CCCC)N3OCCCCNC(CCCCCCCCCCCCCCCCC)=O

Molecular Formula

C36H59N5O2

Molecular Weight

593.89

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhao BG, et al. Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors. J Immunother Cancer. 2014 May 13;2:12.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

TLR7; TLR8

Available Sizes

Frequently Asked Questions

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