Telratolimod
Telratolimod (MEDI9197) is a potent toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity[1].
Product Specifications
CAS Number
[1359993-59-1]
Product Name Alternative
MEDI9197; 3M-052
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Telratolimod.html
Purity
98.85
Solubility
DMSO : 62.5 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=NC2=CC=CC=C2C3=C1N=C(CCCC)N3OCCCCNC(CCCCCCCCCCCCCCCCC)=O
Molecular Formula
C36H59N5O2
Molecular Weight
593.89
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhao BG, et al. Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors. J Immunother Cancer. 2014 May 13;2:12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
TLR7; TLR8
Available Sizes
Curated Selection
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