Maleimide
Product Specifications
UNSPSC Description
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes[1][2].
Target Antigen
ADC Linker
Type
Natural Products
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/maleimide.html
Purity
99.98
Solubility
DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(N1)C=CC1=O
Molecular Weight
97.07
References & Citations
[1]Renault K, et, al. Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies. Bioconjug Chem. 2018 Aug 15;29(8):2497-2513.|[2]Zhang S, et, al. A Maleimide-functionalized Tetraphenylethene for Measuring and Imaging Unfolded Proteins in Cells. Chem Asian J. 2019 Mar 15;14(6):904-909.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W007324/Maleimide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W007324/Maleimide-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
541-59-3
Available Sizes
Curated Selection
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