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FSHR agonist 1

Product Specifications

UNSPSC Description

FSHR agonist 1 is a high affinity and allosteric follicle stimulating hormone receptor (FSHR) agonist with a pEC50 of 7.72. FSHR agonist 1 formes extensive interactions with the TMD to directly activate FSHR[1].

Target Antigen

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/fshr-agonist-1.html

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N(C(C)(C)C)CC)C1=NC(C2=CC=CS2)=C3C4=C(CCN13)C=C(OC)C(OC(C)C)=C4

Molecular Weight

467.62

References & Citations

[1]Jia Duan, et al. Universal mechanism of hormone and allosteric agonist mediated activation of glycoprotein hormone receptors as revealed by structures of follicle stimulating hormone receptor. biorxiv. August 01, 2022.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-150210/FSHR-agonist-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-150210/FSHR-agonist-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1256776-89-2

Available Sizes

Curated Selection

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