CCF10

CCF10 is a peptide sex pheromone that facilitates the transfer of the conjugative plasmid pCF10 from donor bacteria containing the plasmid to recipient bacteria lacking it. It activates the bacterial Opp system, allowing entry into the bacteria and inhibiting the accumulation of (p) ppGpp. By preserving the metabolic activity state of bacteria, cCF10 reduces the formation of persistent bacteria.