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TRAP-14 amide

TRAP-14 amide is a protease-activated receptor (PAR) activating peptide and acts as a PAR agonist, with an EC50 of 24 μM. It induces significant platelet aggregation via ADP and MMP-2 dependent pathways and is insensitive to Aspirin. Additionally, TRAP-14 amide effectively increases the surface expression of glycoprotein (GP) Ib and GPIIb/IIIa, as well as the release of ADP.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Molecular Weight

1738.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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