CIGB-552

CIGB-552 is a cell-penetrating peptide with antitumor properties, exhibiting an IC50 of 23 μM in H460 cells. It increases the level of COMMD1 protein and significantly inhibits the NF-κB signaling pathway. Furthermore, CIGB-552 promotes apoptosis (apoptosis) of tumor cells and induces accumulation of reactive oxygen species (ROS) within them. Additionally, it possesses anti-inflammatory and anti-angiogenic effects. CIGB-552 is applicable in research related to lung and colon cancer.